Female Hormone Research
Estrogen | Estrogen Deficiency Diseases | Menstrual Cycle Preservation
Menopause research has historically been framed as symptom management + safety surveillance, not physiologic replacement with performance endpoints.
We have a large, consistent clinical signal that sustained estradiol in the mid-hundreds (with appropriately cycled progesterone) is associated with the absence of the classic menopause symptom cluster and preservation of high-function physiology. This is measurable in brain, bone, body composition, sleep, cardiometabolic markers, and quality of life. The medical literature has not adequately tested this exposure range in long-term designs. We are building the dataset now.
I’m a clinical hormone professional with a long-duration clinical signal I believe medicine has not properly studied: women maintained for years in a sustained estradiol range roughly consistent with the upper physiologic reproductive range, with appropriately cycled progesterone, often do not develop the brain-and-body symptom cluster commonly labeled ‘menopause.’ This is not a philosophical claim—it is measurable.
We need independent data: standardized estradiol assays, predefined outcomes (brain, sleep, bone, metabolic), and transparent safety monitoring. I am building a registry and seeking academic collaborators, clinicians willing to contribute de-identified data, and funders who want to answer a question that matters to millions of women.
Marie Hoäg, MBA
Advanced Female HRT Educator & Clinical Consultant
Founder, Panacea Sciences
Contact Us To
Volunteer—if you are a woman who would like to participate in clinical trials.
Contribute—if you are a professional interested in helping with research.
Donate—if you would like to financially contribute to the foundation.
Intern—medical or science grad students interested in helping.
Participate—if you are a hormone prescribing physician.
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